Calmex V (Paste)


Size *

"My horse is hot headed in the alley, I tried calmex after using mvp supplements for a year and he walked right in the first time! Love this paste"

- Trinity Overly

 Perfect to use before trailering, showing, or other stressful situations.

  • Promotes a healthy nervous system and supports calmness in horses.  
  • Specially designed for horses that show signs of hyperactivity or nervousness, or horses that are extra responsive to stress in their environment.
  • Beneficial for any horse that is stressed by trailering, vet visits, is easily excitable, or for hot performance horses that become excitable prior to competition.
  • All natural ingredients.
  • Packaged as single, ready to use tubes.

 Suggested use: Use 2-4 hours before trailering, competing, or before or during any stressful situation.

Remove cap and place tip of syringe between the tongue and the side of the mouth. Press the plunger and squeeze the paste into the mouth. The paste comes in a 12ml single dose syringe, which makes it super easy to administer to your horse.


** Due to state regulations, this product is not for sale in the states of California and Vermont. Orders placed containing this item will not ship and will be automatically refunded.



MVP products are manufactured in the USA using the highest quality ingredients with guaranteed analysis. MVP nutritional supplements, including Calmex-V, are trusted and recommended by equine veterinarians, trainers and horse enthusiasts the world over.




 Calmex-V paste contains high levels of active ingredients including Valerian Root and Tryptophan, to help support a healthy nervous system.  Excellent for competition, training and trailering. This convenient paste is ideal for providing extra support in new situations and during times of stress.

This formula may be administered in addition to a daily serving of Calmex or Calmex-V powder.

 *Check competition rulings regarding the use of Valerian Root.








Valerian Root is an herb with specific actions on the nervous system. It helps maintain a healthy nervous system and balance in horses displaying nervous/anxious behavior. **Valerian root is a banned substance in many organizations, always check competition guidelines regarding its usage.

Thiamine (Vitamin B1) plays a role in supporting carbohydrate metabolism and normal muscle and nerve function. Thiamine supplementation has been shown to have a calming effect in horses displaying anxious/nervous behavior as a result thiamine deficiency and/or increased requirements.

Tryptophan is an amino acid, converted by the body into serotonin, melatonin, and other hormones that transmit nerve signals in the brain. Serotonin is the neurotransmitter in the horse’s brain that helps promote feelings of well-being/contentment as well as balanced behavior.

Taurine is an amino acid found in high concentrations in electrically active tissues such as the brain, heart, retina and muscle. It stabilizes membranes and assists in the movement of electrolytes in and out of cells, which is critical for proper nervous system and muscle health. Taurine is necessary for the absorption of fats and vitamins and helps support normal insulin and glucose levels. It can be found in supplements for growing horses, nervous horses and horses with metabolic issues.

Inositol is closely related to the B-vitamin family and is found in nearly every cell in the body. Because of its location within the cell membrane, it plays two major roles: transporting fats and assisting in nerve transmission. By participating in the action of serotonin, a neurotransmitter whose brain levels are known to be a factor in excess anxiety, inositol may be helpful in promoting a healthy balanced behavior in horses.



My gelding is a great horse at home and most of the time when we travel. He has difficulty in large indoor coliseum type arenas. He will do things he normally never do such as hollow/tense his back, spook and cross fire. Will this product help to take the edge off?

MVP:  If your horse is generally well behaved at home, you might consider a calming support product that can be given on an occasional basis, such as Calmex-V Paste, which is designed for use during stressful situations such as travel or clinics. The paste should be administered orally 2 to 4 hours prior to an event, and may be fed in addition to a daily serving of Calmex-V or Calmex for additional support.  *Please note that if you are competing, we do recommend checking your competition rulings regarding the use of valerian root.


My mare seems to be a bit better on Calmex-V paste when we go to a clinic but she still seems agitated, is there anything else that might help her? She just isn’t herself and it seems like she can’t help it.

MVP:  Great question! Your mare could very likely be suffering from gastric upset. Often times this anxious behavior may be due to an increased level of gastric acid produced during periods of stress. We would recommend using the Gastro-Plex paste for as-needed support.  Gastro-Plex™ paste works in part, by coating the stomach lining and in turn provides leverage against the abrasiveness of gastric juices. You can use it with the Calmex-V paste if needed for additional support.


5 out of 5 (2 Reviews)
Trinity Overly Jun 16th 2020


My horse is hot headed in the alley, I tried calmex after using mvp supplements for a year and he walked right in the first time! Love this paste

Elaine Jan 15th 2017

Performs well!

My 10 year old gelding is very anxious! He used to rear and balk before entering the alley. I give him MVPs Calmex V before we run and he goes in AND performs very well!!

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