Calmex-V (Powder)


"I recently started my very anxious gelding on Calmex-V. Within 30 days I have noticed a huge difference in him as far as his demeanor at home and at shows. I highly recommend this product for someone needing to take the edge off without taking the run out of them! "

- Kali Greenlee

Calmex-V contains natural ingredients along with Valerian Root, to help support healthy nervous system.  


New improved formula!  Now with tryptophan!


Calmex-V Paste:  Buy 4 get 1 FREE!






(Enclosed measure approximates 1 oz based on density of product.)

Adult Horses (900-1,100 lbs): Provide 1/2 to 3/4 oz twice daily as needed.








Valerian Root is an herb with specific actions on the nervous system. Valerian re-balances a nervous system
struggling with restlessness and anxiety. Because it also relieves muscle cramps and
spasms associated with tension, it is especially helpful in horses that process anxiety through their muscles.
**Valerian root is a banned substance in many organizations, always check competition guidelines regarding
its usage.

Magnesium (Mg) is a vital macromineral, and it is becoming increasingly recommended by veterinarians for
various treatments in the horse. Because one of the clinical signs of magnesium deficiency is nervousness, it
is added to many calming supplements. Magnesium helps support a normal inflammatory response.
Magnesium may play a role in insulin resistance and equine metabolic syndrome. Within the muscle calcium
and magnesium work antagonistically — calcium causing muscle contraction and magnesium inducing
relaxation. If there is not enough magnesium, muscles tend to spasm

Thiamine, or vitamin B1, plays a vital role in carbohydrate metabolism and nerve transmission. The NRC has set a daily dietary requirement for thiamine because, unlike most of the other B vitamins, microorganisms in the intestine do not make enough thiamine to meet the horse's needs. Fortunately fresh forage and cereal grains are good sources of this vitamin. However, hard-working horses or those on high grain diets may have reduced production of thiamine by intestinal bacteria because of stress or hind gut acidosis. Thiamine supplementation has been shown to have a calming effect in individuals displaying undesirable behavior due to a thiamine deficiency or increased requirements.

Tryptophan is an essential amino acid, which, if lacking in the diet, can cause anxiety. Serotonin is made from
L-Tryptophan and serotonin is the neurotransmitter in the horse’s brain that aids in the feelings of well-being and contentment, to calm and to soothe.

Taurine can be used alone, or with other calming ingredients, for anxious behavior or horses in challenging situations. Also supports heart and muscle function along with liver and nervous system health. It can be found in supplements for growing horses, nervous horses and horses with metabolic issues.

Inositol is one of the lesser known B vitamins and also referred to as vitamin B8. Inositol is critical for messages
sent between different cells, particularly those found in the brain and spinal tissues. Participates in the action of serotonin, a neurotranmitter whose brain levels are known to be a factor in excess anxiety, inositol may be helpful in nervous horses.

The Vitamin B family is made up of several compounds that serve many important roles in the body: protein, fat and carbohydrate metabolism; energy production; proper nerve cell transmission; and cell reproduction and division (especially rapidly dividing ones such as red blood cells). B vitamins include thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), folic acid (B9), cyanocobalamin (B12), choline, biotin, inositol and others are sometimes referred to as B-vitamins. For most of the B-vitamins, microorganisms in the large intestine make all the horse needs. Only thiamine and riboflavin have NRC dietary requirements. However, research suggests B-vitamin supplementation may be beneficial to stabled horses with little access to fresh pasture, heavily exercising horses, pregnant and lactating mares, horses with GI conditions that may interfere with normal gut flora, and any periods of stress (injury, illness, shipping, old age, etc.)



How long after consumption will the ingredients begin to have an effect? I am trying to plan out the best time to ride after feeding this supplement.

MVP:  Calmex-V™ is designed to be fed daily to provide ongoing support for proper nervous system function, helping to manage nervousness and support your horse’s ability to focus. Because this product works by providing nutrients (such as vitamin B1 and magnesium) that your horse’s body needs for a healthy, balanced nervous system, it may take a few weeks before you see the full results of this product. However it does not need to be given at a specific time of day relative to your riding time. If you are looking for a calming supplement that can be given on an occasional basis, you might consider the Calmex-V Paste, which is designed for use as-needed during stressful situations.


Can I give this supplement to a mare who is on Levelor? There is taurine in both, I’m not sure how much is too much.

MVP: A nutrient-based calming supplement like Calmex or Calmex-V may be given in conjunction with a product like Levelor, which supports a healthy hormone balance as these formulas address different aspects of your horse’s health. The amount of taurine and magnesium provided by both products together is considered appropriate for most horses with an otherwise balanced diet. If you have any concerns about using these supplements with your individual horse, we recommend discussing this with your veterinarian.


5 out of 5 (3 Reviews)
Kali Greenlee Jun 15th 2020

This is a game changer for horses with anxiety.

I recently started my very anxious gelding on Calmex-V. Within 30 days I have noticed a huge difference in him as far as his demeanor at home and at shows. I highly recommend this product for someone needing to take the edge off without taking the run out of them!

Theresa Jan 28th 2018

Really helped with anxiety

Tried on my gelding and really helped with his anxiety when I trailer him to different places. Also anxious when we trail ride and has really helped with calming him down.

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